EM Haplotype Frequency Estimates by Race/Ethnicity
Frequencies of HLA-A, B, DRB1 haplotypes were estimated by race/ethnicity from a subset of donors in the NMDP registry. Characteristics of this subset are identified in the table below.
| |
African American / Black |
Asian / Pacific Islander |
Hispanic |
White |
Total |
| Volunteers available |
(N = 412,861) |
(N = 359,423) |
(N = 449,844) |
(N = 2,361,208) |
(N = 3,583,336) |
| Level of DRB1 Typing |
| None |
37,503 (9%) |
40,601 (11%) |
47,771 (11%) |
773,172 (33%) |
899,047 (25%) |
| Serology |
1,600 (<1%) |
2,853 (<1%) |
2,466 (<1%) |
68,379 (3%) |
75,298 (2%) |
| Low Resolution DNA |
53,015 (13%) |
44,561 (12%) |
47,518 (11%) |
171,538 (7%) |
316,632 (9%) |
| Intermediate Resolution DNA |
283,053 (69%) |
251,433 (70%) |
322,175 (72%) |
1,196,807 (51%) |
2,053,468 (57%) |
| Allele(s) determined |
37,690 (9%) |
19,975 (6%) |
29,914 (7%) |
151,312 (6%) |
238,891 (7%) |
Estimated haplotype frequencies are found in the files listed below. Each file format lists the same set of HLA-A, B, and DRB1 allele combinations. Only haplotypes with an observed frequency of at least 1 x 10-6 in at least one of the identified race/ethnic groups have been included.