A-B-DRB1 224 Haplotype Frequencies

EM Haplotype Frequency Estimates by Race/Ethnicity

Frequencies of HLA-A, B, DRB1 haplotypes were estimated by race/ethnicity from a subset of donors in the NMDP registry. Characteristics of this subset are identified in the table below.

	African American / Black	Asian / Pacific Islander	Hispanic	White	Total
Volunteers available	(N = 412,861)	(N = 359,423)	(N = 449,844)	(N = 2,361,208)	(N = 3,583,336)
Level of DRB1 Typing
None	37,503 (9%)	40,601 (11%)	47,771 (11%)	773,172 (33%)	899,047 (25%)
Serology	1,600 (<1%)	2,853 (<1%)	2,466 (<1%)	68,379 (3%)	75,298 (2%)
Low Resolution DNA	53,015 (13%)	44,561 (12%)	47,518 (11%)	171,538 (7%)	316,632 (9%)
Intermediate Resolution DNA	283,053 (69%)	251,433 (70%)	322,175 (72%)	1,196,807 (51%)	2,053,468 (57%)
Allele(s) determined	37,690 (9%)	19,975 (6%)	29,914 (7%)	151,312 (6%)	238,891 (7%)

Estimated haplotype frequencies are found in the files listed below. Each file format lists the same set of HLA-A, B, and DRB1 allele combinations. Only haplotypes with an observed frequency of at least 1 x 10^-6 in at least one of the identified race/ethnic groups have been included.

EM Haplotype Frequency

Readme (TXT)

EM Haplotype Frequency Estimates
Haplotypes (TXT)
Haplotypes (XLS)

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